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The publication of this sixth edition of Applied Biopharmaceutics and Pharmacokinetics represents over 30 years in print. We are grateful to our readers for their loyalty and helpful suggestions throughout the years.
As with the previous editions, we want to continue to maintain our original scope and objectives. This text integrates basic scientific principles with drug product development and clinical pharmacy practice.
Applied Biopharmaceutics & Pharmacokinetics, 7e
The major objective is to provide the reader with a basic and practical understanding of shaegel principles of biopharmaceutics and ahargel that can be applied to drug product development and to pharmackkinetics therapy. This revised and updated edition of the text remains unique in teaching basic concepts that may be applied to understanding complex issues associated with in vivo drug delivery that are essential for safe and efficacious drug therapy.
The primary audience is pharmacy students enrolled in pharmaceutical science courses in pharmacokinetics and biopharmaceutics. This text fulfills course work offered in separate or combined courses in these subjects. Secondary audiences for this textbook are research and development scientists in pharmaceutics, biopharmaceutics, and pharmacokinetics.
There are many improvements in this edition. Bioavailability and Bioequivalenceto reflect the consideration of bioequivalence as an in vivo measure of drug product performance pharmacokinwtics that bioequivalence is important in both brand and generic drug product development. This chapter describes the types of safety and efficacy risks and various means for preventing them including the roles of drug product quality and drug product performance.