Available online at CURCUMA CAESIA ROXB. AND IT’S MEDICINAL. USES: A REVIEW. Sonjit Das, ProdyutMondal and Md. Kamaruz Zaman*. PDF | On Apr 19, , Sonjit Das and others published CURCUMA CAESIA ROXB. AND IT’S MEDICINAL USES: A REVIEW. Black turmeric is known to have certain medicinal values. The curcumin content when I read certain papers, It was very low ~ %. Now I am wondering.

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IARC monograph on the evaluation of carcinogenicity: Micronuclei in circulating erythrocytes: Articles from Toxicology Reports are provided here courtesy of Elsevier.

Materials and methods 2. Pharmacognostic parameters for evaluation of the rhizomes of Curcuma caesia.

Int J Plant Prod. For antigenotoxic studies, animals were divided into eight groups and micronucleus assay was employed and for biochemical analysis serum sample was collected from the blood and SGOT, SGPT analysis was performed. Higher mutagenicity was found when CP was activated with S9 but inhibition of this microsomal activity was observed cudcuma the presence of rhizome extract.

Preliminary mechanistic studies on the smooth muscle relaxant effect of hydroalcoholic extract of Curcuma caesia. Indian J Biochem Biophys. Where, Ab is the absorption of the control and Aa is the absorption of the extract sample. The mechanism caeesia contributes to the antioxidant capacity of phenols and flavanoids include free radical scavenging ability, hydrogen or electron donation ability, chelation of redox active metals ions, modulation of gene expression and interaction with the cell signalling pathways [36].

Hosseinimehr SJ, Karami M.

An increase in the number of micronuclei was observed when treated with CP only as shown in Table 4. Reitman S, Frankel S. Handbook of Medicinal Plants. Analysis of total phenols and other oxidation substrates and antioxidants by means of Folin—Ciocalteu reagent. Micronucleus assay Mice bone marrow micronucleus test was carried out according to. A sensitive and reliable curcuna for the detection of lipid peroxidation in biological tissues.


Statistical analysis The results are presented as the average and S. Mice bone marrow micronucleus test was carried out according to. Pranab Behari MazumderProfessor Pranab Behari Mazumder is a faculty of Department of Biotechnology, assam University, Silchar and his interest is on medicinal plant studies as well microbial related studies. The emerging concepts of cancer is that the cancer cells are unstable and its unstability is brought about by the documentations of cascade of mutations caused by mutagens and suggested that mutagenesis caesix out tumour progression [1].

They were provided standard mice feed. Free Radicals in Biology and Medicine.

Curcuma caesia

Antioxidant properties of phenolic compounds. Am J Clin Pathol. Protein concentration was estimated following. New Central Book Agency; Stimulation of cyclophosphamide-induced pulmonary microsomal lipid peroxidation by oxygen. Antioxidant activity of the aqueous extract of harn jyur Chrysanthemum morifolium Ramat Lebensmi-Wiss Technol.

Curcuma caesia — Vikaspedia

With an ever increasing cause of cancer, it has been recommended to treat with conventional drugs, however because of the side effects caused by the conventional drugs, the research on medicinal plants has been intensified due to their less adverse and toxic effects.

Antimutagenic effects of flavonoids, chalcones and structurally related compounds on the activity of 2-aminomethylimidazo [4,5-f] quinoline IQ and other heterocyclic amine mutagens from cooked food.

One, plant-derived compounds are complex in nature which are difficult to synthesize in the laboratory and are helpful in the prevention of onset of cancer by its antioxidant activity and stimulation of the immune system,[ 35 ] second, plant-derived compounds are used for prevention and decreasing side effects of conventional cancer treatments.


Bergmeyer J, Grab M, editors. Antioxidant and antimutagenic activities of pomegranate peel extracts. J Environ Pathol Toxicol Oncol. This page was last edited on 6 Decemberat The study was conducted on 25—30 g body weight male Swiss albino mice. Int J Sci Res Publ. The antioxidant properties of phytochemicals are linked to their ability to scavenge free radicals generated either endogenously or by exogenous agents.

Author information Copyright and License information Disclaimer. Antimutagenicity testing For the experiment with S9 mix, 0. Cyclophosphamide-induced nephrotoxicity, genotoxicity, and damage in kidney genomic DNA of Swiss albino mice: Ethanolic extract reduces the mutagenicity caused by indirect acting mutagen cyclophosphamide by In conclusion, the present study has shown for the first time that C. The quenching of free radical activity of different extracts were determined by spectrophotometric method against 2,2-diphenylpicryl hydrazyl DPPH following [25].

Cyclophosphamide induced lipid peroxidation and changes in cholesterol content: SUMMARY Cancer is characterized by uncontrolled growth of cells and much research has been done for the past several years from various disciplines for the treatment of cancer but till now no therapy has been discovered. Further studies are needed to isolate the active principles present in it. Antimutagenic activity of Aspergillus awamori -fermented black soyabean response to stimulated digestive juice treatments and its antimutagenic mechanisms.

Principles of oncologic pharmacotherapy; pp. Sulfur free radical reactivity with curcumin as reference for evaluating antioxidant properties of medicinal Zingiberales. Percentage of inhibition was calculated using the formula given below: